腹腔镜下输卵管切开取胚缝合术与输卵管部分切除术治疗输卵管异位妊娠对患者性激素水平的影响

王秀丽

文章摘要

腹腔镜下输卵管切开取胚缝合术与输卵管部分切除术治疗输卵管异位妊娠对患者性激素水平的影响

Effect of laparoscopic salpingectomy and partial salpingectomy for ectopic tubal pregnancy on sex hormone levels in patients

投稿时间：2023-05-19 修订日期：2024-01-22

DOI：

中文关键词: 输卵管切开取胚缝合术输卵管部分切除术异位妊娠性激素

英文关键词: Tubal incision, embryo extraction and suture Partial salpingectomy Ectopic pregnancy Sex hormone

基金项目:

作者	单位	邮编
王秀丽^*	邳州东大医院妇产科江苏邳州 221300	221300

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中文摘要:

【摘要】目的：探究腹腔镜下输卵管切开取胚缝合术治疗输卵管异位妊娠对患者性激素水平、并发症、妊娠结局的影响。方法：选择2022年1月-12月期间于邳州东大医院治疗的78例输卵管异位妊娠患者，依据术式不同分为两组，39例/组。采取腹腔镜下输卵管部分切除术治疗的患者纳入对照组，采取腹腔镜下输卵管切开取胚缝合术方案的患者纳入观察组。比较两组手术相关指标（手术和下床时间，术中出血量，住院用时），出、人院后6个月的性激素水平，并发症及术后1年妊娠情况。结果：观察组手术时间（69.39±5.10）min长于对照组，术中出血量（45.33±10.43）mL少于对照组，下床活动时间（10.32±1.85）h、住院时间（7.21±0.85）d短于对照组（P＜0.05）；出院时及出院后6个月，观察组E2水平（40.34±5.14）pg/mL和（43.35±4.89）pg/mL、AMH水平（3.43±0.40）ng/mL和（3.91±0.55）ng/mL均高于对照组，FSH水平（6.35±0.98）IU/L和（5.21±0.89）IU/L、LH水平（7.43±1.01）IU/L和（6.43±0.95）IU/L均低于对照组（P＜0.05）；相比于对照组，观察组总并发症发生率更低（P＜0.05）；观察组宫内妊娠率69.23%高于对照组的33.33%（P＜0.05）；观察组再次异位妊娠率及未受孕率分别为12.82%、17.95%，低于对照组的33.33%、33.33%（P＜0.05）。结论：综上所述，输卵管异位妊娠选择腹腔镜下输卵管切开取胚缝合术，疗效显著，可改善临床各项指标，使得性激素水平恢复正常，减少并发症的发生，预防再次异位妊娠率。

英文摘要:

[Abstract] Objective: To explore the impact of laparoscopic fallopian tube incision, embryo retrieval, and suture surgery for the treatment of ectopic pregnancy in the fallopian tubes on patients' sex hormone levels, complications, and pregnancy outcomes. Method: 78 patients with ectopic pregnancy in the fallopian tubes who were treated at Dongda Hospital in Pizhou from January to December 2022 were selected and divided into two groups based on different surgical procedures, 39 cases per group. The control group of 39 cases underwent laparoscopic partial salpingectomy, while the observation group of 39 cases underwent laparoscopic salpingotomy, embryo retrieval, and suture. Compare the surgical related indicators (surgery and bedtime, intraoperative bleeding, hospitalization time), sex hormone levels, complications, and 1-year pregnancy status between the two groups of patients at 6 months after discharge and hospitalization. Result: The observation group operating time was (69.39±5.10) minutes longer than control group, and the intraoperative blood loss was (45.33±10.43) mL less than control group. The time to get out of bed was (10.32±1.85) hours, and the hospital stay was (7.21±0.85) days shorter than control group (P<0.05); At discharge and 6 months after discharge, the observation group E2 levels of (40.34±5.14) pg/mL and (43.35±4.89) pg/mL, AMH levels of (3.43±0.40) ng/mL and (3.91±0.55) ng/mL were higher than control group. the observation group levels of FSH (6.35±0.98) IU/L and (5.21±0.89) IU/L, LH (7.43±1.01) IU/L and (6.43±0.95) IU/L were lower than control group (P < 0.05); The observation group total incidence of complications was 5.13% lower than 25.64% in control group (P<0.05); The observation group intrauterine pregnancy rate was 69.23% was higher than 33.33% in control group (P<0.05); The rates of recurrent ectopic pregnancy and non conception in the observation group were 12.82% and 17.95%, respectively, lower than the 33.33% and 33.33% in control group (P<0.05). Conclusion: In summary, laparoscopic fallopian tube incision, embryo retrieval, and suture surgery is an effective method for ectopic pregnancy. It can improve various clinical indicators, restore normal sex hormone levels, reduce complications, and prevent the occurrence of ectopic pregnancy again.

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