| Abstract: Objective: To explore the effect of post-operative rehabilitation training combined with life guidance on promoting the recovery of patients with gastric cancer. Methods: A total of 80 patients with gastric cancer after surgery from January 2020 to December 2021 were selected and randomly divided into groups. The control group (n=40) received routine postoperative intervention, and the observation group (n=40) received postural rehabilitation. Training combined with life guidance intervention was used to compare the recovery of gastrointestinal function and the incidence of complications between the two groups, and the European Cancer Research and Treatment Quality of Life Scale was used to evaluate the quality of life of the patients before and after the intervention. RESULTS: The time of intestinal peristalsis recovery, exhaust gas, drinking water and liquid food intake in the observation group were (1.82±0.60) d, (3.12±1.21) d, (4.62±1.05) d, and (6.73±2.13) d respectively, all shorter than The control group; the complication rate of the observation group was 5.00%, which was 27.50% lower than that of the control group; the scores of each dimension of quality of life in the observation group after intervention: cognitive function (58.87±6.09), physical function (64.32±5.73), emotional function ( 65.72±6.29) points, role function (53.71±6.63) points, social function (46.82±6.19) points, all higher than the control group, the difference was statistically significant (P<0.05). Conclusion: Postural rehabilitation training combined with life guidance intervention for patients after gastric cancer surgery can improve the gastrointestinal function and quality of life, and is beneficial to reduce the risk of complications.