文章摘要
920例女性外阴阴道念珠菌病菌种分布及药敏结果分析
Analysis of species distribution and drug sensitivity of female vulvovaginal candidiasis(with 920 cases)
投稿时间:2021-08-11  修订日期:2021-09-28
DOI:
中文关键词: 外阴阴道念珠菌病  菌种分布  药物敏感性
英文关键词: vulvovaginal candidiasis  Strain distribution  Drug sensitivity
基金项目:
作者单位邮编
黄坤 盘锦市大洼区人民医院检验科 124200
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中文摘要:
      目的:探究女性外阴阴道念珠菌病(vulvovaginal candidiasis, VVC)菌种分布及耐药情况。方法:将2018年1月-2020年12月在盘锦市大洼区人民医院妇科门诊就诊的920例VVC患者作为本次研究对象,对所有患者进行念珠菌菌种鉴定、药敏试验,并对结果进行分析。结果:920例患者中,VVC菌种由多至少依次为白色念珠菌(74.35%)、热带念珠菌(11.41%)、光滑念珠菌(8.37%)、近平滑念珠菌(3.04%)、克柔念珠菌(2.83%)。药敏试验显示,伊曲康唑、酮康唑、氟康唑对部分菌种具有一定的耐药性,而两性霉素B、制霉菌素、5-氟胞嘧啶则对绝大部分念珠菌敏感。结论:女性VVC中,大部分为白色念珠菌,且不同菌种对抗真菌药物的耐药性不同,因此,明确女性VVC的菌种、药敏试验结果,能为医生治疗提供可靠的实验室依据,以提高疗效。
英文摘要:
      Objective: To explore the species distribution and drug resistance of female vulvovaginal candidiasis. Methods: A total of 920 patients with vulvovaginal candidiasis treated in the gynecological clinic of Dawa District People"s Hospital of Panjin City from January 2018 to December 2020 were taken as the research object. Candida species identification and drug sensitivity test were carried out for all patients, and the results were analyzed. Results: Among 920 patients, the species of vulvovaginal Candida were Candida albicans (74.35%), Candida tropicalis (11.41%), Candida smooth (8.37%), Candida near smooth (3.04%) and Candida Creutzfeldt (2.83%). The drug sensitivity test showed that itraconazole, ketoconazole and fluconazole were resistant to some strains, while amphotericin B, nystatin and 5-fluorocytosine were sensitive to most Candida. Conclusion: Most of female vulvovaginal candidiasis are Candida albicans, and different strains have different drug resistance to antifungal drugs. Therefore, clarifying the strains and drug sensitivity test results of female vulvovaginal candidiasis can provide reliable laboratory basis for doctors" treatment and improve the curative effect.
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