文章摘要
健脾消积汤联合化疗治疗胃癌患者的疗效分析
Analysis of the effect of Jianpi Xiaoji Decoction combined with chemotherapy on patients with gastric cancer
投稿时间:2021-01-27  修订日期:2021-01-27
DOI:
中文关键词: 胃癌  健脾消积汤  化疗  联合治疗  疗效  免疫功能  不良反应
英文关键词: gastric cancer  Jianpi Xiaoji Decoction  chemotherapy  combination therapy  curative effect  immune function  adverse reactions
基金项目:
作者单位邮编
孙以民 山东省无棣县人民医院 251900
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中文摘要:
      【摘要】目的 分析健脾消积汤联合化疗治疗胃癌患者的疗效。 方法 从2018年8月至2020年8月收治的胃癌患者中进行筛选,选择80例患者进行研究,按照就诊顺序分组。两组患者均接受了SOX化疗方案,研究组患者加用健脾消积汤治疗。比较两组患者治疗4个月后的中医症候积分、KPS评分、CD4+、CD4+/CD8+水平、不良反应发生率。 结果 治疗4个月后研究组中医症候积分更低,KPS评分以及CD4+、CD4+/CD8+水平更高,两组结果具有统计学差异(P<0.05);对照组的不良反应发生率为32.5%,研究组不良反应发生率为12.50%,研究组的不良反应发生率与对照组相比明显更低,数据具有统计学差异(P<0.05)。 结论 采用健脾消积汤联合化疗治疗胃癌患者疗效优于单一化疗治疗的效果,能够明显改善患者免疫功能与健康状况,安全性良好。
英文摘要:
      【Abstract】Objective To analyze the efficacy of Jianpi Xiaoji Decoction combined with chemotherapy in the treatment of patients with gastric cancer. Methods Screening was performed from patients with gastric cancer admitted from August 2018 to August 2020, and 80 patients were selected for the study and grouped according to the order of visits. Patients in both groups received SOX chemotherapy, and patients in the study group were treated with Jianpi Xiaoji Decoction. The TCM syndrome score, KPS score, CD4+, CD4+/CD8+ levels, and incidence of adverse reactions were compared between the two groups of patients after 4 months of treatment. Results After 4 months of treatment, the TCM syndrome score of the study group was lower, and the KPS score and CD4+, CD4+/CD8+ levels were higher. The results of the two groups were statistically different (P<0.05); the incidence of adverse reactions in the control group was 32.5%. The incidence of adverse reactions in the study group was 12.50%, and the incidence of adverse reactions in the study group was significantly lower than that in the control group. The data was statistically different (P<0.05). Conclusion The effect of Jianpi Xiaoji Decoction combined with chemotherapy in the treatment of gastric cancer patients is better than that of single chemotherapy. It can significantly improve the immune function and health status of patients, and has good safety.
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